5
Evaluate

Health Impact Analysis

Project Overview

"Conduct a comprehensive health impact assessment for an air quality intervention in your school or community, quantifying the expected health benefits using concentration-response functions."

Health Impact Assessment Framework

  1. Characterize baseline exposure: Current pollutant concentrations and population exposed
  2. Define intervention scenario: Expected concentration changes from intervention
  3. Select health endpoints: Mortality, hospitalizations, asthma exacerbations, etc.
  4. Apply concentration-response functions: From epidemiological literature
  5. Calculate attributable cases: Health events prevented or caused
  6. Monetize health benefits: Economic valuation (optional)

The Health Impact Function

Delta_Y = Y0 x (1 - exp(-beta x Delta_C)) x Pop

  • Delta_Y: Change in health outcomes (cases prevented)
  • Y0: Baseline incidence rate (cases per person per year)
  • beta: Concentration-response coefficient (from epidemiology)
  • Delta_C: Change in concentration (ug/m3)
  • Pop: Exposed population

Linear approximation (for small changes): Delta_Y = Y0 x beta x Delta_C x Pop

Concentration-Response Coefficients

Health EndpointBeta (per 10 ug/m3 PM2.5)Source
All-cause mortality0.06 (6% increase)Krewski et al. 2009
Cardiovascular mortality0.09-0.12Pope et al. 2004
Hospital admissions (respiratory)0.02Zanobetti et al. 2009
Asthma ED visits0.05-0.08Various meta-analyses
School absences0.03-0.04Gilliland et al. 2001

Project Requirements

Part 1: Exposure Assessment (30%)

  • Characterize current air quality in your setting
  • Identify exposed population (size, demographics)
  • Estimate exposure duration and concentration
  • Document data sources and assumptions

Part 2: Intervention Analysis (30%)

  • Define a realistic intervention
  • Estimate concentration reduction
  • Apply health impact functions
  • Calculate cases prevented for multiple endpoints

Part 3: Uncertainty Analysis (20%)

  • Identify sources of uncertainty
  • Calculate range using high/low estimates
  • Discuss confidence in results

Part 4: Policy Brief (20%)

  • Summarize findings for decision-makers
  • Compare costs to health benefits
  • Make evidence-based recommendations

Example Calculation

Scenario: Installing HEPA air cleaners in a school

  • Population: 500 students
  • Baseline PM2.5: 15 ug/m3
  • Post-intervention PM2.5: 8 ug/m3
  • Delta_C = 7 ug/m3 reduction
  • Baseline asthma-related absences: 50 per year (100 per 1000 students)

Calculation:

Cases prevented = Y0 x beta x Delta_C x Pop

= 0.1 x 0.004 x 7 x 500 = 1.4 asthma absences prevented per year

Note: This is one endpoint. A complete HIA would include multiple endpoints (respiratory infections, academic performance, etc.).

Assessment Rubric

CriterionExcellent (4)Proficient (3)Developing (2)Beginning (1)
Data QualityRigorous data with documented sourcesGood data with most sourcesLimited data documentationPoor data quality
MethodologyCorrect HIA framework, appropriate CRFsMinor methodological issuesSignificant gaps in approachFramework not applied
UncertaintyComprehensive uncertainty analysisAdequate uncertainty discussionLimited uncertainty considerationNo uncertainty analysis
CommunicationClear, professional, compelling policy briefClear presentationUnclear in placesDifficult to follow

Unit Summary

This unit has explored how air pollution causes disease across multiple organ systems - from the acute inflammation of asthma to the chronic destruction of COPD, from cardiovascular events to cancer. Understanding these mechanisms and applying quantitative risk assessment tools empowers us to make evidence-based decisions about air quality interventions. The health impact assessment framework provides a systematic approach for translating scientific knowledge into policy action.

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